Functionalization of Particle Surface

Plasma-based Surface Functionalization of Polystyrene Substrate

The method to modify the surface of polystyrene (PS) substrate for stable and versatile biomolecule immobilization was developed, which consists of two steps: 1) surface treatment by argon plasma irradiation to introduce hydroxyl group on PS and 2) covalent immobilization of vinylmethyleter-maleic acid copolymer (VEMAC) through a coupling reaction between hydroxyl group on plasma-irradiated PS ...

Facile Surface Functionalization of Hydrophobic Magnetic Nanoparticles

Nonpolar phase synthesized hydrophobic nanocrystals show attractive properties and have demonstrated prominent potential in biomedical applications. However, the preparation of biocompatible nanocrystals is made difficult by the presence of hydrophobic surfactant stabilizer on their surfaces. To address this limitation, we have developed a facile, high efficiency, single-phase and low-cost meth...

Surface Functionalization of Monodisperse Magnetic Nanoparticles

We present a systematic methodology to functionalize magnetic nanoparticles through surface-initiated atom-transfer radical polymerization (ATRP). The magnetite nanoparticles are prepared according to the method proposed by Sun et al. (2004), which leads to a monodisperse population of ~ 6 nm particles stabilized by oleic acid. The functionalization of the nanoparticles has been performed by tr...

Surface Functionalization of Exosomes Using Click Chemistry

A method for conjugation of ligands to the surface of exosomes was developed using click chemistry. Copper-catalyzed azide alkyne cycloaddition (click chemistry) is ideal for biocojugation of small molecules and macromolecules to the surface of exosomes, due to fast reaction times, high specificity, and compatibility in aqueous buffers. Exosomes cross-linked with alkyne groups using carbodiimid...

Investigating the Effect of Various Oxidizing Agents on the Surface Functionalization of Microporous Polypropylene Membranes